Alcohol Intolerance: Symptoms, Sudden Onset & Later in Life Intolerance


The term “alcohol intolerance” becomes key in deciphering these reactions. Unlike allergies, which involve the immune system, intolerances arise when the body lacks the necessary enzymes to digest and eliminate alcohol. Unusual symptoms that may leave one questioning whether the drink in hand is a source of enjoyment or distress. It’s very difficult for consumers to know whether an alcoholic drink contains allergens or ingredients they’re intolerant to.

However, if you’re allergic to an ingredient found in certain alcoholic drinks, dishes which contain that drink are not safe to eat. When we drink alcohol, an enzyme in our bodies called alcohol dehydrogenase (ADH) breaks it down into a compound called acetaldehyde. Another enzyme, aldehyde dehydrogenase (ALDH), then turns acetaldehyde into non-toxic acetic acid (vinegar). Rarely, severe pain after drinking alcohol is a sign of a more serious disorder, such as Hodgkin’s lymphoma. Alcohol intolerance with these conditions is rare but can occur.

Low aldehyde dehydrogenase

“Ethanol as a cause of hypersensitivit[…]ic beverages.” Clinical & Experimental Allergy, August 2002. But there aren’t any tests for sulfite or histamine sensitivity. The difference between the what causes alcohol intolerance two has to do with how the body reacts to alcohol. If someone requires support with their alcohol use, they can speak with a doctor to discuss the recommended guidelines for alcohol intake.

can you become alcohol intolerant

However, it’s always a good idea to be checked by a doctor—especially if you’ve noticed any other concerning symptoms in your general health. Sudden onset alcohol intolerance is when an alcohol intolerance that was not present from birth occurs abruptly later on in life. Most people with ALDH2 deficiency will notice some effects from the first time they take a drink, but there’s often no known reason as to why an alcohol intolerance develops. In some cases, reactions may also result from an allergy to a grain such as corn or wheat in alcoholic beverages. If a person combines alcohol with certain medications, this may also cause a reaction.

Why Your Overall Tolerance For Alcohol May Drop

This is why even a small amount of alcohol impacts our judgment and ability to drive, while a moderate amount can impair our ability to form memories. Typically, alcohol withdrawal symptoms happen for heavier drinkers. Alcohol withdrawal can begin within hours of ending a drinking session. Aldehyde is toxic, and buildup is one of the key reasons people develop symptoms of a hangover.

Grapes, wheat, hops, and gluten may be present in the alcoholic beverage, which is causing the problems, instead of the reasons mentioned above. Approximately 20 to 30 minutes after alcohol consumption, sufferers will feel a hot or tingling sensation around the eyes, cheeks, forehead, and ears. Wine is reportedly one of the main culprits for this reaction. Wine contains tannins (which are found in the skin of grapes) which many people react negatively to, including experiencing diarrhea. This can leave you feeling sick and dehydrated, which can also make hangovers the following day even worse.

Can You Mix Prednisone and Alcohol? The Risks of Drinking on Steroids

Alcohol intolerance is a real condition, but it can sometimes be confused with other related conditions, such as allergies or drug interactions with alcohol. Having an alcohol intolerance is a genetic condition that means your body cannot process alcohol correctly. In some cases, reactions can be triggered by a true allergy to a grain such as corn, wheat or rye or to another substance in alcoholic beverages. Alcohol intolerance is caused by a genetic condition in which the body can’t break down alcohol efficiently.